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Evidence is increasing that most addiction without exception is related to problems with the brain's reward center, particularly the mesolimbic system. This section of the problem regulates reward responses in acquiring food and sex, along with nurturing infants and children. One of the most important neurotransmitters associated with reward responses, both when they malfunction and after they function properly, is dopamine. What makes opiates unique is that it, among other neurotransmitters modulates "the level of dopamine released in in reaction to a stimulus"(Bostwick & Bucci, 2008).
Using two separate drugs to shed pounds can be very effective you will find combinations in front of the FDA now awaiting approval. When dealing with weight loss and the people who go through it one should err to the side of caution and allow FDA do its job and demand some study be done in order that the public recognizes the side effects and dangers of the medications before we drive them. Keep in mind that drug companies will be in business to generate income and that they would say anything to keep people on his or her medications.
Researchers discovered that participants taking this drug for the year, dropped excess weight within a month and have kept the body weight off throughout the 56 weeks of the study. Contrave is often a combination with the drugs naltrexone and bupropion, which usually reflect a fresh trend of weight-loss drugs which might be made up of many active ingredient, which can make them far better and safer.
Combo-pilling may be the newest fad or better yet the newest into the future under scrutiny and therefore it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that using a combination of pills is becoming popular will be the fact that as of right now there are no long term prescription slimming capsules that have been approved by the FDA apart from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications and some of the combinations are actually rejected or have yet to be approved by the FDA.
Seizures certainly are a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug can also raise blood pressure levels and heartrate, and mustn't be used in those with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy while using drug.
The FDA also warned that Contrave can raise hypertension and pulse rate and must not be used in patients with uncontrolled high blood pressure levels, as well as by a person with heart-related and cerebrovascular (circulation dysfunction impacting the brain) disease. Patients using a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes having a boxed warning to alert medical professionals and patients to the increased chance of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stopping smoking.
--Participating in support groups that help the family in the addict recover (like Al-Anon or Nar-Anon).